JNJ 10191584 maleate
CAS No. 869497-75-6
JNJ 10191584 maleate ( JNJ 10191584 maleate salt; VUF6002 maleate )
产品货号. M27640 CAS No. 869497-75-6
histamine H4 receptor silent antagonist
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥1021 | 有现货 |
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5MG | ¥1482 | 有现货 |
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10MG | ¥1831 | 有现货 |
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25MG | ¥4026 | 有现货 |
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50MG | ¥5856 | 有现货 |
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100MG | ¥7995 | 有现货 |
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200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称JNJ 10191584 maleate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述histamine H4 receptor silent antagonist
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产品描述histamine H4 receptor silent antagonist(In Vitro):JNJ 10191584 maleate shows 540-fold selectivity to H4 receptor(Ki = 14.1 μM).(In Vivo):In spared nerve injury mice, JNJ 10191584 maleate (10 μg/μL; intra locus coeruleus administration) abolishes VUF-induced anti-allodynic effect and prevents the anti-allodynic effect of VUF 8430. JNJ 10191584 maleate (6 μg/mouse; intrathecal administration) prevents VUF 8430-induced anti-allodynic effect.
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同义词JNJ 10191584 maleate salt; VUF6002 maleate
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通路Others
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靶点Other Targets
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受体DNA/RNA Synthesis
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研究领域——
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适应症——
化学信息
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CAS Number869497-75-6
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分子量394.8
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分子式C17H19ClN4O5
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纯度>98% (HPLC)
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溶解度——
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SMILESOC(=O)\C=C\C(O)=O.CN1CCN(CC1)C(=O)c1nc2ccc(Cl)cc2[nH]1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Hassan AE, et al. 6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases. Bioorg Chem. 2016 Apr;65:9-16.
产品手册
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