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JNJ 10191584 maleate

CAS No. 869497-75-6

JNJ 10191584 maleate ( JNJ 10191584 maleate salt; VUF6002 maleate )

产品货号. M27640 CAS No. 869497-75-6

histamine H4 receptor silent antagonist

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥1021 有现货
5MG ¥1482 有现货
10MG ¥1831 有现货
25MG ¥4026 有现货
50MG ¥5856 有现货
100MG ¥7995 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    JNJ 10191584 maleate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    histamine H4 receptor silent antagonist
  • 产品描述
    histamine H4 receptor silent antagonist(In Vitro):JNJ 10191584 maleate shows 540-fold selectivity to H4 receptor(Ki = 14.1 μM).(In Vivo):In spared nerve injury mice, JNJ 10191584 maleate (10 μg/μL; intra locus coeruleus administration) abolishes VUF-induced anti-allodynic effect and prevents the anti-allodynic effect of VUF 8430. JNJ 10191584 maleate (6 μg/mouse; intrathecal administration) prevents VUF 8430-induced anti-allodynic effect.
  • 同义词
    JNJ 10191584 maleate salt; VUF6002 maleate
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    DNA/RNA Synthesis
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    869497-75-6
  • 分子量
    394.8
  • 分子式
    C17H19ClN4O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    OC(=O)\C=C\C(O)=O.CN1CCN(CC1)C(=O)c1nc2ccc(Cl)cc2[nH]1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Hassan AE, et al. 6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases. Bioorg Chem. 2016 Apr;65:9-16.
产品手册
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